Preheat oven to 375 degrees F. Lightly coat a 9x5-inch loaf pan with cooking spray, or line with no-stick foil.
Separate biscuits and place on a lightly floured surface. Gently pull each biscuit horizontally into two layers, making 16 dough rounds. Using hands, press out into 4-inch rounds. Place one cheese cube on each round; stretch biscuit dough up around filling to cover completely. Pinch edges together tightly to seal securely. Repeat with remaining rolls and cheese. Place filled and sealed biscuit balls in the prepared pan.
Drizzle balls with melted butter and sprinkle with sesame seeds. Bake 26 to 30 minutes or until golden brown. Remove from pan and serve hot.