Well it really depends on what kind of rose you are talking about. If you are asking about Hybrid Teas, Floribundas, or Grandifloras, you can't propagate them because they are actually grafted plants (a flowering top part that's grafted on a tough, wild rootstock). So, if you take cuttings off the top they won't be hardy enough to grow without a graft. For other types of roses, use new growth to propagate. Cut off 4 to 6 inches, remove the leaves on all but the very top, and dip the stem in rooting hormone. Then, place the cutting in sterile vermiculite or perlite and keep it slightly moist in humid conditions. There's no guarantee they'll root this way, but it's worth trying if you have a rose you can't find in the stores that you want to propagate. But remember, if your rose is a grafted type, don't bother trying to do this. You can tell if it's a grafted rose if it has a large knob or bump where the main stem and the roots meet."