Experts and BHG readers answer.
What to do with Powdery Mildew on Pumpkin Leaves
Hi, You can spray the entire vine with the fungicide following label directions. This won't cure the affected leaves but should protect new foliage. I would not remove the infected leaves because that could defoliate the plant. I'd leave them in place, and remove them if they die or when the plants finish in the fall.